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Dr Alfred Amambua-Ngwa


Career Development Fellow


Medical Research Council Unit, The Gambia

Alfred’s research focus is on malaria population genomics with a particular interest in determining genome-wide signatures of selection for markers of immunity and drug resistance in Plasmodium falciparum. His current research on Plasmodium genetics provides a strong link between the CGGH and the malaria research programme in The Gambia led by Umberto d’Alessandro. He also supports molecular detection and genotyping in several studies on bacterial and viral infections. For his post-doctoral project with David Conway, Alfred studied Gambian P. falciparum isolates using deep sequencing data to investigate signatures of balancing selection, with the aim of identifying new targets for functional and immunological investigation. This work was done in collaboration with the MalariaGEN P. falciparum Community Project. This study has since been published in PLoS Genetics. Alfred is also a member of the Plasmodium Diversity Network Africa (PDNA).