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  • 24
    Sep '12

    Royal Society honours Dr Sam Kariuki

    Dr Sam Kariuki, Chief Research Scientist and Head of Department at the Centre for Microbiology Research at the Kenya Medical Research Institute (KEMRI) in Nairobi and a Wellcome Trust Sanger Institute International Fellow, has received the prestigious Royal Society Pfizer Award.

  • 17
    Sep '12

    Decoding the human genome

    The Encyclopedia of DNA Elements (ENCODE) project set out to identify all the functional elements within the human genome. As a result of this large-scale, global collaboration between 440 researchers in 32 labs, 80% of components of the human genome are now associated with at least one biochemical function.

  • 16
    Sep '12

    SAO associated with reduced risk of vivax malaria in children

    Three independent studies undertaken in Papua New Guinea revealed strong associations between the SAO genetic defect (SLC4A1Δ27) and protection against P. vivax malaria in infants and children. The way in which the SAO defect infers protection is still unknown. The findings suggest that P. vivax may have contributed to unique host-parasite adaptations in the region.

  • 16
    Sep '12

    Whole-genome sequencing of P. vivax field isolates

    A recent study reports the whole genome sequencing of five P. vivax isolates taken directly from blood samples of infected patients in Cambodia and Madagascar, as well as the Belem strain that is adapted to survive in monkeys. Each patient was found to be infected with multiple vivax strains. Researchers identified a catalogue of 80,000 SNPs, which can be used for large-scale genotyping and association mapping studies.

  • 28
    Jun '12

    Bill & Melinda Gates Foundation award grant for genomic analysis in large-scale study of artemisinin resistance in P. falciparum

    The emergence of artemisinin resistance (ART-R) in Plasmodium falciparum malaria parasites, recently reported in Cambodia and Thailand, has become one of the most pressing global health emergencies. If ART-R is not effectively contained, its spread from South-East Asia could undermine antimalarial treatment globally, jeopardizing eradication efforts and causing a massive death toll.

  • 14
    Jun '12

    Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

    A new technique has been developed to identify hotspots of malaria parasite evolution and track the rise of malarial drug resistance, faster and more efficiently than ever before.

  • 07
    May '12

    GEM 2012

    We are looking forward to attending the upcoming 2012 Wellcome Trust Conference on Genomic Epidemiology of Malaria (GEM), June 10-13th at the Welcome Trust Conference Centre on the Genome Campus (home of The Sanger Institute) in Hinxton.

  • 01
    May '12

    Chris Spencer awarded Wellcome Trust Career Development Fellowship

    Chris Spencer has been awarded a Wellcome Trust Career Development Fellowship to work on statistical methods for understanding the genetics of human disease phenotypes. Chris did a DPhil in population genetics with Gil McVean before joining Peter Donnelly’s group as...

  • 13
    Apr '12

    Global Bioethics Summer School

    The Ethox Centre is pleased to announce that together with its partners at the Wellcome Trust Major Overseas Programmes in Kenya, Malawi, Thailand, South Africa and Vietnam, they are once again running their annual one-week global health ethics summer school focussing on the ethical aspects of collaborative research in developing countries.

  • 06
    Mar '12

    Philip Bejon awarded MRC Clinical Scientist Fellowship

    Philip Bejon has been awarded an MRC Clinical Scientist Fellowship to study the heterogeneity of malaria transmission, particularly in Kenya but also in other parts of Africa.