The frontline treatment for uncomplicated malaria in Western Cambodia is the drug combination dihydroartemisinin (DHA) – piperaquine (PPQ). In response to increasing reports that this treatment was failing in the region, researchers tested samples collected from three locations in Cambodia to investigate whether the parasites were becoming resistant to DHA, PPQ or both drugs. They tested these samples for known molecular markers and for...
The Centre for Genomics and Global Health's specialist course, 'Reviewing Genomic Research', has been translated into French and Portguese. Designed for those responsible for reviewing genomics research projects, the course: defines genomic research; examines the types of research questions being addressed; illustrates how genomic research differs from other types of research; and, introduces specific ethical considerations when reviewing...
A worldwide collaboration of researchers has shown that resistance to the frontline antimalarial drug – artemisinin – can be identified by surveying the genomes of parasite populations. The effectiveness of this key drug is weakening, threatening hundreds of thousands of lives.
(Source: Wellcome Trust) The global burden of dengue infection is more than triple current estimates from the World Health Organization, according to a multinational study published in the journal 'Nature'. The research has created the first detailed and up-to-date map of dengue distribution worldwide, enabling researchers to estimate the total numbers of people affected by the virus globally, regionally and nationally. The findings will help...
The Centre for Genomics and Global Health’s specialist course, ‘Reviewing Genomic Research’, is now available on the Global Health Reviewers website.
Designed for those responsible for reviewing genomics research projects, the course:
(15 Nov 2012, University of Oxford): A new study has demonstrated how DNA sequencing techniques can map tuberculosis (TB) outbreaks, allowing the spread of disease to be tackled more quickly and effectively.
The 1000 Genomes Project has released the full sequence of 1,092 human genomes from 14 populations in Europe, the Americas, East Asia and Africa.
Humans can — and regularly do — travel much further than the mosquitoes that carry malaria, potentially allowing the parasites to hitch a ride into new territories. Researchers used detailed cell phone records to map the location of nearly 15 million Kenyan mobile phone subscribers over a year period.