Seven leading African researchers are the recipients of major funding from the Wellcome Trust and the Department for International Development (DFID) to establish cutting-edge research and training programmes across the continent.
The Pf3k Consortium has made its third public data release, the first to include data on all samples in the pilot phase of the project. Consisting of sample information, analysis BAMs and preliminary baseline genotypes for 2,512 samples collected from major malaria-endemic regions in Africa and Asia, this represents one of the largest collections of open access Plasmodium falciparum genomes in the world. This release comes at a time when the...
Study identifies complex genetic architecture behind drug resistance, providing a reminder of how crucial surveillance and elimination programmes are
A study of the way malaria parasites behave when they live in human red blood cells has revealed that they can rapidly change the proteins on the surface of their host cells during the course of a single infection in order to hide from the immune system.
These findings provide deep insights into the stage of the parasite lifecycle that is responsible for causing severe illness, and could explain how the parasites are able to stay in...
The first major dataset from the Anopheles gambiae 1000 Genomes (Ag1000G) project has been released. Comprising data on genetic variation between 765 mosquitoes from 8 countries spanning sub-Saharan Africa, it is one of the largest public datasets on genome variation in any species and a key resource for malaria research.
The Plasmodium Diversity Network Africa (PDNA) has published an analysis of genetic variation in 1,212 P. falciparum samples collected from across 12 African countries.
A study of genetic variants associated with cases of severe malaria has successfully integrated data from almost 30,000 participants across multiple locations in Africa, Asia and Oceania. The study has achieved insights into the evolutionary battle between the malaria parasite and human populations that could not have been achieved by smaller studies in each location.
Scientists are poised to capture data that will help support efforts to track and respond to the drug-resistant malaria parasites in Africa.
Drug-resistant malaria parasites have spread to critical border regions of South-east Asia, seriously threatening global malaria control and elimination programmes, according to a study published in the 'New England Journal of Medicine'.